当研究室(遺伝子治療・再生医学分野)では、再生医療、遺伝子治療、バイオテクノロジーと先端医学開発の研究を行っています。

論文 - 鹿児島大学大学院医歯学総合研究科 先進治療科学専攻 運動機能修復学講座 遺伝子治療・再生医学分野

nature2003Takahashi K, Mitsui K, Yamanaka Y.

Role of  E-Ras in promoting tumor-like properties of mouse embryonic stem cell.

 

Nature 423 541-545. 2003

 


 

ico treatiseTokuzawa Y, Kaiho E, Maruyama M, Takahashi K, Mitsui K, Maeda M, Niwa H, Yamanaka S.

Fbx15 is a novel target of Oct3/4 but is dispensable for ES cell self-renewal and mouse development.

 

Mol Cell Biol. 23 2699-2708. 2003

 


 

1 s2.0 s0003497520x00063 cov150hFukunaga M, Takamori S, Hayashi A, Shirouzu K, Kosai K.

Adenoviral herpes simplex virus thymidine kinase gene therapy in an orthotopic lung cancer model.

 

Ann Thorac Surg 73: 1740-1746, 2002

 


 

cardiovasc 2002Aoyama T, Takemura G, Maruyama R, Kosai K, Takahashi T, Koda M, Hayakawa K, Kawase Y, Minatoguchi S, Fujiwara H.

Molecular mechanisms of non-apoptosis by Fas stimulation alone versus apoptosis with an additional actinomycin D in cultured cardiomyocytes.

 

Cardiovasc Res 55:787-798, 2002

 


 

m jem 206 1 coverYoshida T, Hanada T, Tokuhisa T, Kosai K, Sata M, Kohara M, Yoshimura A.

Activation of STAT3 by the Hepatitis C virus core protein leads to cellular transformation.

 

J. Exp. Med. 196: 641-653, 2002

 


 

jci108 12 coverShouda T, Yoshida T, Hanada T, Wakioka T, Oishi M, Miyoshi K, Komiya S, Kosai K, Hanakawa Y, Hashimoto K, Nagata K, Yoshimura A.

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis.

 

J Clin Invest 108: 1781-1788, 2001

 


 

sciencs2000Miyado K, Yamada G, Yamada S, Hasuwa H, Nakamura Y, Ryu F, Suzuki K, Kosai K, Inoue K, Ogura A, Okabe M, Mekada E.

Requirement of CD9 on the egg plasma membrane for fertilization.

 

Science 287: 321-324, 2000

 


 

ico treatiseKuratani S, Satokata I, Blum M, Komatsu Y, Haraguchi R, Nakamura S, Suzuki K, Kosai K, Mass R, Yamada G.

Middle ear defects associated with the double knockout mutation of murine Goosecoid and Msx1 genes.

 

Cell. Mol. Biol. 45: 589-599, 1999

 


 

ico treatiseKosai K, Matsumoto K, Funakoshi H, Nakamura T.

Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice.

 

Hepatology 30: 151-159, 1999

 


 

bbrc1998Kosai K, Matsumoto K, Nagata S, Tsujimoto Y, Nakamura T.

Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor.

 

Biochem. Biophys. Res. Commun. 244: 683-690, 1998

 


 

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鹿児島大学大学院医歯学総合研究科 遺伝子治療・再生医学分野

医学部基礎研究棟3階
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