当研究室(遺伝子治療・再生医学分野)では、再生医療、遺伝子治療、バイオテクノロジーと先端医学開発の研究を行っています。

論文 - 鹿児島大学大学院医歯学総合研究科 先進治療科学専攻 運動機能修復学講座 遺伝子治療・再生医学分野

cardiovasc 2002Aoyama T, Takemura G, Maruyama R, Kosai K, Takahashi T, Koda M, Hayakawa K, Kawase Y, Minatoguchi S, Fujiwara H.

Molecular mechanisms of non-apoptosis by Fas stimulation alone versus apoptosis with an additional actinomycin D in cultured cardiomyocytes.

 

Cardiovasc Res 55:787-798, 2002

 


 

m jem 206 1 coverYoshida T, Hanada T, Tokuhisa T, Kosai K, Sata M, Kohara M, Yoshimura A.

Activation of STAT3 by the Hepatitis C virus core protein leads to cellular transformation.

 

J. Exp. Med. 196: 641-653, 2002

 


 

jci108 12 coverShouda T, Yoshida T, Hanada T, Wakioka T, Oishi M, Miyoshi K, Komiya S, Kosai K, Hanakawa Y, Hashimoto K, Nagata K, Yoshimura A.

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis.

 

J Clin Invest 108: 1781-1788, 2001

 


 

sciencs2000Miyado K, Yamada G, Yamada S, Hasuwa H, Nakamura Y, Ryu F, Suzuki K, Kosai K, Inoue K, Ogura A, Okabe M, Mekada E.

Requirement of CD9 on the egg plasma membrane for fertilization.

 

Science 287: 321-324, 2000

 


 

ico treatiseKuratani S, Satokata I, Blum M, Komatsu Y, Haraguchi R, Nakamura S, Suzuki K, Kosai K, Mass R, Yamada G.

Middle ear defects associated with the double knockout mutation of murine Goosecoid and Msx1 genes.

 

Cell. Mol. Biol. 45: 589-599, 1999

 


 

ico treatiseKosai K, Matsumoto K, Funakoshi H, Nakamura T.

Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice.

 

Hepatology 30: 151-159, 1999

 


 

bbrc1998Kosai K, Matsumoto K, Nagata S, Tsujimoto Y, Nakamura T.

Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor.

 

Biochem. Biophys. Res. Commun. 244: 683-690, 1998

 


 

nucleic 1998Timchenko NA, Wilde M, Kosai KI, Heydari A, Biyeu TA, Finegold MJ, Mohamedali K, Richardson A, Darlington GJ.

Regenerating livers of old rats contain high levels of C/EBPalpha that correlate with altered expression of cell cycle associated proteins.

 

Nucleic acids Res. 26:3293-3299, 1998

 


 

human gene1998Kosai K, Finegold MJ, Thi-Huynh BT, Tewson M, Ou CN, Bowles N, Woo SL, Schwall RH, Darlington GJ.

Retrovirus-mediated in vivo gene transfer in the replicating liver using recombinant hepatocyte growth factor without liver injury or partial hepatectomy.

 

Human Gene Ther. 9: 1293-1301, 1998

  


 

chest1997Kwong YL, Chen S-H, Kosai K, Finegold MJ, Woo SL.

Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer.

 

Chest. 112: 1332-1337, 1997

 


 

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鹿児島大学大学院医歯学総合研究科 遺伝子治療・再生医学分野

医学部基礎研究棟3階
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