当研究室(遺伝子治療・再生医学分野)では、再生医療、遺伝子治療、バイオテクノロジーと先端医学開発の研究を行っています。

論文 - 鹿児島大学大学院医歯学総合研究科 先進治療科学専攻 運動機能修復学講座 遺伝子治療・再生医学分野

int. j. oncol. 24Nagano S, Yuge K, Fukunaga M, Terazaki Y, Fujiwara H, Komiya S, Kosai K.

Gene Therapy eradicating distant disseminated micro-metastases by optimal cytokine expression in the primary lesion only -novel concepts for successful cytokine gene therapy.

 

Int. J. Oncol. 24: 549-558, 2004

 


 

clin cancer2004Ikoma T, Takahashi T, Nagano S, Li Y-M, Ohno Y, Ando K, Fujiwara T, Fujiwara H and Kosai K.

A definitive role of RhoC in metastasis of orthotopic lung cancer in mice.

 

Clin Cancer Res. 10; 1192-1200, 2004

 


 

 

 

ico treatiseTsuneoka M, Umata T, Kimura H, Koda Y, Nakajima M, Kosai K, Takahashi T, Takahashi Y, Yamamoto A.

c-myc induces autophagy in rat 3Y1 fibroblast cells.

 

Cell Struct Funct. 28: 195-204, 2003

 


 

circ.2003.107.issue 19.coverLi Y, Takemura G, Kosai K, Yuge K, Nagano S, Esaki M, Goto K, Takahashi T, Hayakawa K, Koda M, Kawase Y, Maruyama R, Okada H, Minatoguchi S, Mizuguchi H, Fujiwara T, Fujiwara H.

Postinfarct treatment with an adenoviral vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice.

 

Circulation. 107: 2499-2506, 2003

 


 

pediatr cardiol 24Himeno W, Akagi T, Furui A, Maeno Y, Ishii M, Kosai K, Murohara T, Kato H.

Increased angiogenic growth factor in cyanotic congenital heart disease.

 

Pediatr Cardiol, 24: 127-32. 2003

 


 

hepatology37Terazaki Y, Yano S, Yuge K, Nagano S, Fukunaga M, Guo ZS, Komiya S, Shirouzu K, Kosai, K.

An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice.

 

Hepatology 37:155-163. 2003

 


 

cell2003Mitsui K, Tokuzawa Y, Segawa K, Murakami M, Itoh H, Takahashi K, Maeda M, Yamanaka S.

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.

 

Cell 113 631-642. 2003

 


 

nature2003Takahashi K, Mitsui K, Yamanaka Y.

Role of  E-Ras in promoting tumor-like properties of mouse embryonic stem cell.

 

Nature 423 541-545. 2003

 


 

ico treatiseTokuzawa Y, Kaiho E, Maruyama M, Takahashi K, Mitsui K, Maeda M, Niwa H, Yamanaka S.

Fbx15 is a novel target of Oct3/4 but is dispensable for ES cell self-renewal and mouse development.

 

Mol Cell Biol. 23 2699-2708. 2003

 


 

1 s2.0 s0003497520x00063 cov150hFukunaga M, Takamori S, Hayashi A, Shirouzu K, Kosai K.

Adenoviral herpes simplex virus thymidine kinase gene therapy in an orthotopic lung cancer model.

 

Ann Thorac Surg 73: 1740-1746, 2002

 


 

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鹿児島大学大学院医歯学総合研究科 遺伝子治療・再生医学分野

医学部基礎研究棟3階
(エレベーターを出てから左の教室です)

鹿児島県鹿児島市桜ヶ丘8丁目35-1
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