当研究室(遺伝子治療・再生医学分野)では、再生医療、遺伝子治療、バイオテクノロジーと先端医学開発の研究を行っています。

論文 - 鹿児島大学大学院医歯学総合研究科 先進治療科学専攻 運動機能修復学講座 遺伝子治療・再生医学分野

pnasSuzuki K, Mitsui K, Aizawa E, Hasegawa K, Kawase E, Yamagishi T, Shimizu Y, Suemori H, Nakatsuji N, Mitani K.

Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors.

 

Proc Natl Acad Sci USA.105 13781-6. 2008

 


 

bbrc2007

Ijichi N, Ikeda K, Horie-Inoue K, Yagi K, Okazaki Y, and Inoue S.
Estrogen-related receptor α modulates the expression of adipogenesis-related genes during adipocyte differentiation.

 

Biochem Biophys Res Commun. 358: 813-818, 2007

 


 

 

j card failgif Chen XH, Minatoguchi S, Kosai K, Yuge K, Takahashi T, Arai M, Wang N,
 Misao Y, Lu C, Onogi H, Kobayashi H, Yasuda S, Ezaki M, Ushikoshi H,
 Takemura G, Fujiwara T, Fujiwara H.

 In vivo hepatocyte growth factor gene transfer reduces myocardial
 ischemiareperfusion injury through its multiple actions.

 

                         J Card Fail. 13(10):874-883, 874-883, 2007

  


 

ico treatise

Takayama K, Kaneshiro K, Tsutsumi S, Horie-Inoue K, Ikeda K, Urano T, Ijichi N, Ouchi Y, Shirahige K, Aburatani H, and Inoue S.
Identification of novel androgen response genes in prostate cancer cells by coupling chromatin immunoprecipitation and genomic microarray analysis.

 

Oncogene 26: 4453-4463, 2007.

 


 

1 s2.0 s1525001606x0103x cov200hTakahashi T, Kawai T, Ushikoshi H, Nagano S, Oshika H, Inoue M, Kunisada T, Takemura G, Fujiwara H, Kosai K.

Identification and isolation of embryonic stem cell-derived target cells by adenoviral conditional targeting.

 

Mol Ther. 14, 673-683. 2006

 


 

int j oncolMurofushi Y, Nagano S, Kamizono J, Takahashi T, Fujiwara H, Komiya S, Matsuishi T, and Kosai K.

Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: A promising implication of telomerase-dependent targeted cancer gene therapy.

 

Int J Oncol.  29: 681-688, 2006

 


 

ico treatiseKuge H, Ohashi K, Yokoyama T, Kanehiro H, Hisanaga M, Koyama F, Bumgardner GL, Kosai K, Nakajima Y.

Genetic modification of hepatocytes towards hepatocyte transplantation and liver tissue engineering.

Cell Transplant. 15:1-12, 2006

 


 

 

j hepatology Khai NC, Takahashi T, Ushikoshi H, Nagano S, Yuge K, Esaki M, Kawai T,
 Goto K, Murofushi Y, Fujiwara T, Fujiwara H, Kosai K.

 In vivo hepatic HB-EGF gene transduction inhibits Fas-induced liver injury
 and induces liver regeneration in mice: A comparative study to HGF.

 

 J. Hepatol. 44:1046-1054, 2006

 


 

cardiovasc respngMisao Y, Takemura G, Arai M, Sato S, Suzuki K, Miyata S, Kosai K, Minatoguchi S, Fujiwara T, Fujiwara H.

Bone marrow-derived myocyte-like cells and regulation of repair-related cytokines after bone marrow cell transplantation.

 

Cardiovasc Res. 69: 476-490, 2006

 


 

ico treatiseKagawa T., Takemura G., Kosai K., Murata I., Ohno T., Takahashi T., Esaki M., Maruyama R., Fujiwara T., Ohashi H., Fujiwara H.

Hepatocyte growth factor gene therapy slows down the progression of diabetic nephropathy in db/db mice.

 

Nephron Physiol. 102: 92-102, 2006

 


 

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鹿児島大学大学院医歯学総合研究科 遺伝子治療・再生医学分野

医学部基礎研究棟3階
(エレベーターを出てから左の教室です)

鹿児島県鹿児島市桜ヶ丘8丁目35-1
TEL.099-275-5219
FAX.099-265-9721

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