1.     Ishihara Y, Nakamura K, Nakagawa S, Okamoto Y, Yamamoto M, Furukawa T, Kawahara K^＊. 共著,Nucleolar Stress Response via Ribosomal Protein L11 Regulates Topoisomerase Inhibitor Sensitivity of P53-Intact Cancers. Int J Mol Sci. 2022. 23(24):p15986. (^＊:Corresponding Author )

2.     Nakagawa S, Kawahara K^＊, Okamoto Y^＊, Kodama Y, Nishikawa T, Kawano Y, Furukawa T. 共著, Association between Dysfunction of the Nucleolar Stress Response and Multidrug Resistance in Pediatric Acute Lymphoblastic Leukemia. Cancers (Basel). 2022. 14(20):p5127. (^＊:Corresponding Author )

3.     Miyao S, Saito K, Oshima R, Kawahara K, Nagahama M. 共著, MTR4 adaptor PICT1 functions in two distinct steps during pre-rRNA processing. Biochem Biophys Res Commun. 2022, 637. 203-209.

4.     Nagata T, Minami K, Yamamoto M, Hiraki T, Idogawa M, Fujimoto K, Kageyama S, Tabata K, Kawahara K, Ueda K, Kato Y, Ikeda R, Komatsu M, Tanimoto A, Furukawa T, Sato M.　 共著, BHLHE41/DEC2 expression induces autophagic cell death in lung cancer cells and is associated with favorable prognosis for patients with lung adenocarcinoma. Int J Mol Sci. 2021. 22(21):p11509.

5.     Jingushi K, Aoki M, Ueda K, Kogaki T, Tanimoto M, Monoe Y, Ando M, Matsumoto T, Minami K, Ueda Y, Kitae K, Hase H, Nagata T, Harada-Takeda A, Yamamoto M, Kawahara K, Tabata K, Furukawa T, Sato M, Tsujikawa K, 共著, ALKBH4 promotes tumourigenesis with a poor prognosis in non-small-cell lung cancer. Sci Rep. 2021. 11(1):p8677.

6.     Kogaki T, Ohshio I, Ura H, Iyama S, Kitae K, Morie T, Fujii S, Sato S, Nagata T, Takeda AH, Aoki M, Ueda K, Minami K, Yamamoto M, Kawahara K, Furukawa T, Sato M, Ueda Y, Jingushi K, Tozuka Z, Saigusa D, Hase H, Tsujikawa K, 共著, Development of a highly sensitive method for the quantitative analysis of modified nucleosides using UHPLC-UniSpray-MS/MS. J Pharm Biomed Anal. 2021. 197: p113943.

7.     Shinagawa N, Minami K, Ishida T, Hijioka H, Yamamoto M, Kawahara K, Furukawa T, Nakamura N, 共著, Combination of hydroxyurea and tranilast suppresses gemcitabine resistance induced by ribonucleotide reductase M1 in gemcitabine-resistant cells, Oral Sci Int. 2021.18: pp169-177.

8.     Kawahata T^〇 , Kawahara K^〇,*, Shimokawa M, Sakiyama A,, Shiraishi T, Minami K, Yamamoto M, Shinsato Y, Arima K, Hamada T, Furukawa T., 共著, Involvement of ribosomal protein L11 expression in sensitivity of gastric cancer against 5-FU. Oncol Lett,19(3) pp2258-2264, 2020. (^○:These two authors are contributed equally to this work as a first author, ^＊:Corresponding Author )　

9.     Higa　N, Shinsato Y, Kamil M, Hirano T, Takajo T, Shimokawa M, Minami K, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K and Arita K., 共著, Formin-like 1 (FMNL1) Is Associated with Glioblastoma Multiforme Mesenchymal Subtype and Independently Predicts Poor Prognosis. Int J Mol Sci. 20(24) p6355. 2019.

10.  Hirano T, Shinsato Y, Tanabe K, Higa N, Kamil M, Kawahara K, Yamamoto M, Minami K, Shimokawa M, Arigami T, Yanagita S, Matushita D, Uenosono Y, Ishigami S, Kijima Y, Maemura K, Kitazono I, Tanimoto A, Furukawa T & Shoji Natsugoe., 共著, FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer. Oncogenesis. 9 (2) p13, 2020.

11.  Nishizawa Y, Ikeda R, Yamamoto M , Kawahara K, Shinsato Y, Minami K , Nitta M , Terazono H , Akiyama S, Furukawa T, Takeda Y., 共著, 5-Aza-2-deoxycytidine Enhances the Sensitivity of 5-Fluorouracil by Demethylation of the Thymidine Phosphorylase Promoter. Anticancer Res. 39 (8), pp4129-4136, 2019.

12.  Hirono T, Jingushi K, Nagata T, Sato M, Minami K, Aoki M, Takeda AH, Umehara T, Egawa H, Nakatsuji Y, Kitae K, Ueda Y, Hase H, Yamamoto M, Shinsato Y, Kawahara K, Furukawa T, Tsujikawa K., 共著, MicroRNA-130b functions as an oncomiRNA in non-small cell lung cancer by targeting tissue inhibitor of metalloproteinase-2. Sci Rep. 9(1):p6956. 2019.

13.  Kamil M, Shinsato Y, Higa N, Hirano T, Idogawa M, Takajo T, Minami K, Shimokawa M, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K, Arita K., 共著, High filamin-C expression predicts enhanced invasiveness and poor outcome in glioblastoma multiforme. Br J Cancer. 120(8):pp819-826. 2019.

14.  Kamijo Y^〇, Kawahara K^〇*, Yoshinaga T , Kurata H , Arima K, Furukawa T^＊., 共著, A novel isolation method for cancer prognostic factors via the p53 pathway by a combination of in vitro and in silico analyses, Oncoscience, 5(3-4), pp88-98, 2018. (^○:These two authors are contributed equally to this work as a first author, ^＊:Corresponding Author )

15.  Tabata S,Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K, Shinsato Y, Minami K, Saijo A, Toyoda Y, Hanibuchi M, Nishioka Y, Sone S, Esumi H, Tomita M, Soga T, Furukawa T^*,Akiyama S., 共 著, Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells. Sci Rep. 8(1), p6760, 2018.

16.  Li Y, Kobayashi K, Murayama K, Kawahara K, Shima Y, Suzuki A, Tani K, Takahashi A, 共著,  FEAT enhances INSL3 expression in testicular Leydig cells. Genes Cells. 23(11), pp952-962, 2018.

17.  Furukawa T, Tabata S, Yamamoto M, Kawahara K, Shinsato Y, Minami K, Shimokawa M, Akiyama SI., 共著, Thymidine phosphorylase in cancer aggressiveness and chemoresistance. Pharmacol Res. 132, pp.15-20, 2018

18.  Tabata S, Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K, Shinsato Y, Minami K, Saijo A, Hanibuchi M, Nishioka Y, Sone S, Esumi H, Tomita M, Soga T, Furukawa T, Akiyama SI., 共著, Thymidine Catabolism as a Metabolic Strategy for Cancer Survival. Cell Rep. 19(7), pp1313-1321, 2017. 

19.  Tanabe K, Shinsato Y, Furukawa T, Kita Y, Hatanaka K, Minami K, Kawahara K, Yamamoto M, Baba K, Mori S, Uchikado Y, Maemura K, Tanimoto A, Natsugoe S., 共著, Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma. Oncotarget. 8(4), pp6353-6363. 2017

20.  河原康一、古川龍彦, 共著,核 小体によるp53制御とがん治療薬開発の新展開, 実験医学, 35, pp2365-2367, 2017

21.  Moinuddin FM, Shinsato Y, Komatsu M, Mitsuo R, Minami K, Yamamoto M, Kawahara K, Hirano H, Arita K, Furukawa T., 共著, ATP7B expression confers multidrug resistance through drug sequestration. Oncotarget. 7(16), pp22779-90. 2016.

22.  Murata Y, Kotania T, Supriatn Y, Kitamura Y, Imada S, Kawahara K, Nishio M, Daniwijay E.D, Sadakata H, Kusakari S, Mori M, Kanazawa Y, Saito Y, Okawa K, Takeda-Morishita M, Okazawa H, Ohnishi H, Azuma T, Suzuki A, and Matozaki T., 共著, The protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium. Proc. Natl. Acad. Sci. USA. 112(31): pp4264-71, 2015.

23.  Minami K, Shinsato Y, Yamamoto M, Takahashi H, Zhang S, Nishizawa Y, Tabata S, Ikeda R, Kawahara K, Tsujikawa K, Chijiiwa K, Yamada K, Akiyama S, Pérez-Torras S, Pastor-Anglada M, Furukawa T, Takeda Y., 共著, Ribonucleotide reductase is an effective target to overcome gemcitabine resistance in gemcitabine-resistant pancreatic cancer cells with dual resistant factors. J Pharmacol Sci. 127(3): pp319-25, 2015.

24.  河原康一、単著, 核小体 ストレス応答機構による腫瘍化進展制御と抗がん治療戦略, JAMTTC News Letter, 19,  p84, 2015

25.  河原康一、古川龍彦, 共著,核 小体ストレス応答と腫瘍化進展制御―新たな抗がん治療薬開発を目指して., 医学のあゆみ., 254 , pp375-381, 2015　

26.  Minami K, Kamijo Y, Nishizawa Y, Tabata S, Horikuchi F, Yamamoto M, Kawahara K, Shinsato Y, Tachiwada T, Chen ZS, Tsujikawa K, Nakagawa M, Seki N, Akiyama S, Arima K, Takeda Y, Furukawa T., 共著, Expression of ABCB6 Is Related to Resistance to 5-FU, SN-38 and Vincristine. Anticancer Res. 34(9): pp4767-73, 2014.

27.  Maehama T, Kawahara K, Nishio M, Suzuki A, Hanada K., 共著, Nucleolar Stress Induces Ubiquitination-Independent Proteasomal Degradation of PICT1. J. Biol. Chem, 289(30): pp20802-20812, 2014,

28.  Okamura K, Takayama K, Kawahara K, Harada T, Nishio M, Otsubo K, Ichijo K, Kohno M, Iwama E, Fujii A, Ota K, Koga T, Okamoto T, Suzuki A, Nakanishi Y ., 共著, PICT1 expression is a good prognostic factor in non-small cell lung cancer. ONCOSCIENCE 1(5): p375, 2014.

29.  Shinsato Y, Furukawa T, Yunoue S, Yonezawa H, Minami K, Nishizawa Y, Ikeda R, Kawahara K, Yamamoto M, Hirano H, Tokimura H, and Arita K., 共著, Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma. Oncotarget, 4(12): pp2261-70, 2013.

30.  Uchi R, Kogo R, Kawahara K, Sudo T, Yokobori T, Eguchi H, Sugimachi K, Maehama T, Mori M, Suzuki A, Komune S, Mimori K., 共著, PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression. Br J Cancer. 109(8): pp2199-206, 2013.

31.  Liao J, Marumoto T, Yamaguchi S, Okano S, Takeda N, Sakamoto C, Kawano H, Nii T, Miyamato S, Nagai Y, Okada M, Inoue H, Kawahara K, Suzuki A, Miura Y, Tani K., 共著, Inhibition of PTEN Tumor Suppressor Promotes the Generation of Induced Pluripotent Stem Cells. Molecular Therapy, 21(6): pp1242-1250, 2013.

32.  Miyoshi K , Yanagi S , Kawahara K, Nishio M, Tsubouchi H, Imazu Y, Koshida R, Matsumoto N, Taguchi A, Yamashita S, Suzuki A, and Nakazato M., 共著, Epithelial Pten Controls Acute Lung Injury and Fibrosis by Regulating Alveolar Epithelial Cell Integrity. Am J Respir Crit Care Med, 187(3): pp262-75. 2013.

33.  河原康一., 単著, 核小体ス トレス応答によるp53-MDM2経路の制御., 生化学, 85, pp152-9, 2013　

34.  Nishio M, Hamada K^〇, Kawahara K^〇, Sasaki M, Noguchi F, Chiba S, Mizuno K, Suzuki SO, Dong Y, Tokuda M, Morikawa T, Hikasa H, Eggenschwiler J, Yabuta N, Nojima H, Nakagawa K, Hata Y, Nishina H, Mimori K, Mori M, Sasaki T, Mak TW, Nakano T, Itami S, Suzuki A., 共著, Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. J Clin Invest, 122(12): pp4505-18, 2012 (^〇:These two authors are contributed equally to this work as a second author).

35.  Suzuki A, Kogo R, Kawahara K, Sasaki M, Nishio M, Maehama T, Sasaki T, Mimori K, Mori M., 共著, A new PICTure of nucleolar stress., Cancer Sci. 103, pp632-7, 2012

36.  河原康一, 西尾美希, 佐々 木雅人, 前濱朝彦, 佐々木雄彦, 古後龍之介, 三森功士,森 正樹, 鈴木 聡.,  共著, PICT1による核 小体ストレス経路を介したp53と腫瘍進展制御-腫 瘍予後マーカーや今後の創薬応用に向けて-, 遺伝子医学MOOK, pp22,260-5, 2012

37.  Kogo R, Shimamura T, Mimori K, Kawahara K, Imoto S, Sudo T, Tanaka F, Shibata K, Suzuki A, Komune S, Miyano S, and Mori M., 共著, Long non-coding RNA HOTAIR regulates Polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res, 71(20): pp6320-6, 2011.

38.  Sasaki M^〇, Kawahara K^〇, Nishio M, Mimori K, Kogo R, Hamada K , Itoh B, Wangjia J, Komatsu Y, Yang R.Y, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Prives C, Nakano T, Mak W.T, Sasaki T, Maehama T, Mori M and Suzuki A., 共 著, Regulation of the MDM2-p53 Pathway and Tumor Growth by PICT1/GLTSCR2 via Nucleolar RPL11. Nature Medicine, 17(8): pp944-51, 2011 (^〇:These two authors are contributed equally to this work as a first author),

39.  Inoue-Narita T, Hamada K, Sasaki T, Hatakeyama S, Fujita S, Kawahara K, Sasaki M, Kishimoto H, Eguchi S, Kojima I, Beermann F, Kimura T, Osawa M, Itami S, Mak TW, Nakano T, Manabe M, Suzuki A., 共著, Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis. Cancer Res, 68(14): pp5760-8, 2008.

40.  Kuroda S, Nishio M, Sasaki T, Horie Y, Kawahara K, Sasaki M, Natsui M, Matozaki T, Tezuka H, Ohteki T, Forster I, Mak TW, Nakano T, Suzuki A., 共著, Effective clearance of intracellular Leishmania major in vivo requires Pten in macrophages. Eur J Immunol,38(5): pp1331-40,2008.

41.  Kawahara K, Hashimoto M, Bar-On P, Ho GJ, Crews L, Mizuno H, Rockenstein E, Imam SZ, Masliah E., 共著, alpha-Synuclein aggregates interfere with Parkin solubility and distribution: role in the pathogenesis of Parkinson disease. J. Biol. Chem,283(11): pp6979-87,2008.

42.  河原康一、佐々木雄彦、西尾美希、鈴木聡., 共著, が ん抑制遺伝子PTEN異常による各種疾患～PTEN欠 損マウスが教えてくれたもの～.,　生化学, 80, pp1017-25, 2008

43.  Yanagi S, Kishimoto H, Kawahara K, Sasaki T, Sasaki M, Nishio M, Yajima N, Hamada K, Horie Y, Kubo H, Whitsett JA, Mak TW, Nakano T, Nakazato M, Suzuki A., 共著, Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. J Clin Invest,117(10): pp2929-40,2007.

44.  Kishimoto H, Ohteki T, Yajima N, Kawahara K, Natsui M, Kawarasaki S, Hamada K, Horie Y, Kubo Y, Arase S, Taniguchi M, Vanhaesebroeck B, Mak TW, Nakano T, Koyasu S, Sasaki T, Suzuki A., 共著, The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells. Blood,109(8): pp3316-24,2007.

45.  河原康一、濱田浩一、佐々木雄彦、鈴木聡., 共著, PTEN/PI3K経 路による血管制御., 医学のあゆみ, 27, pp480-485, 2007　

46.  Tsuruta H, Kishimoto H, Sasaki T, Horie Y, Natsui M, Shibata Y, Hamada K, Yajima N, Kawahara K, Sasaki M, Tsuchiya N, Enomoto K, Mak TW, Nakano T, Habuchi T, Suzuki A., 共著, Hyperplasia and carcinomas in Pten-deficient mice and reduced PTEN protein in human bladder cancer patients. Cancer Res, 66(17), pp8389-96,2006.

47.  Hashimoto M, Kawahara K, Bar-On P, Rockenstein E, Crews L, Masliah E. , 共著,  The Role of alpha-synuclein assembly and metabolism in the pathogenesis of Lewy body disease., J Mol Neurosci, 24, pp343-52, 2004

48.  Kawahara K, Morishita T, Nakamura T, Hamada F, Toyoshima K, and Akiyama T., 共著,  Downregulation of beta-catenin by The Colorectal Tumor Suppressor APC Requires Association with Axin and beta-catenin. J. Biol. Chem,275(12), pp8369-8374.,2000.

49.  Nakamura T, Hamada F, Ishidate T, Anai K, Kawahara K, Toyoshima K and Akiyama T., 共著, Axin, an inhibitor of the Wnt signaling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level. Genes.Cells,3(6), pp395-403,1998.