鹿児島大学大学院医歯学総合研究科 健康科学専攻 人間環境学講座 疫学・蘭h医学

Research研究内容

主な研究
●環境疫学(重金属、放射線、火山活動など)
 Environmental epidemiology on heavy metals, radiation and volcanic activity
●癌の疫学 Cancer epidemiology
●地域保健と労働衛生・予防医学 Community health, occupational health and preventive medicine
●ウイルス関連がんの疫学 Epidemiology of virus related cancer


主な研究費取得状況
【郡山千早】
●科学研究費(基盤研究(B))平成28年度〜平成30年度(分担)
 鯨・マグロ類多食集団における高濃度メチル水銀曝露の健康影響の解明及び介入研究
●厚生労働科学研究費(成育疾患克服等次世代育成基盤研究事業(健やか世代育成総合研究事業))
 平成29年度〜令和元年度(分担)HTLV-1母子感染予防に関するエビデンス創出のための研究
●革新的技術課発・緊急展開事業(うち地域戦略プロジェクト)平成29年度〜令和元年度(分担)
 血合肉すり身化技術による海外向け和食ヘルスケア食品の開発
●労災疾病臨床研究事業費補助平28年度 〜 令和4年度(分担)
 溶接作業者の溶接ヒュームばく露(個人ばく露と生体内ばく露)と健康影響の関係に関する疫学的研究
●科学研究費 国際共同研究加速基金(国際共同研究強化(B)平成31年度 〜令和4年度(分担)
 災害多発アジア3カ国における学童のヘルスリテラシー向上:クリエイティブヘルス介
●科学研究費 基盤研究C令和4年度 〜令和6年度(代表)
 日本人コホート集団を対象とした水銀曝露と循環器系疾患リスクの評価
●学術変革領域研究(学術研究支援基盤形成)令和4年度(分担)
 コホート・生体試料支援プラットフォーム
●令和2年度経営戦略経費 令和2年度経費新型コロナウイルス追跡調査

【田ノ上史郎】
●科学研究費助成事業 基盤研究(C)  平成29年度〜令和1年度 (代表)
 高フルクトース食による腸内細菌叢構成異常が肝炎症や発癌、癌進展に及ぼす影響の解析

【上床 太心】
●科学研究費(挑戦萌芽) 平成29年度〜令和4年度
 他職種協働による認知機能・自動車運転技能評価と包括的支援の効果の検証
●科学研究費 基盤研究(挑戦萌芽)平成26年度〜平成28年度
 母子保健および少子化対策は、いかなるソーシャルキャピタルを活用すべきか

【ドゥルワ アティラ】

主な研究実績
1.Ishidou Y, Koriyama C, Kakoi H, Setoguchi T, Nagano S, Hirotsu M, Yamamoto Y, Yokouchi M, Komiya S: Predictive factors of mortality and deterioration in performance of activities of daily living after hip fracture surgery in Kagoshima, Japan. Geriatrics and Gerontology International, 2017 Mar; 17(3):391-401.

2.Tsuji M, Koriyama C, Yamamoto M, Anan A, Shibata E, Kawamoto T: The association between maternal psychological stress and inflammatory cytokines in allergic young children. PeerJ, 2016 Jan 18;4:e1585.

3.Ordonez P, Nandakumar A, Koriyama C, Yamamoto M, Akiba S: Cytotoxic effect of NF-kB inhibitors in combination with anti-herpes agents on Epstein-Barr virus-positive gastric carcinoma in vitro. Molecular Medicine Reports, 2016 Sep; 14(3): 2359-67.

4.Yoshimoto K, Anh HT, Yamamoto A, Koriyama C, Ishibashi Y, Tabata M, Nakano A, Yamamoto M: Simple analysis of total mercury and methylmercury in seafood using heating vaporization atomic absorption spectrometry. Journal of Toxicological Sciences, 2016;41: 489-500.

5.Fujio S, Takano K, Arimura H, Habu M, Bohara M, Hirano H, Hanaya R, Nishio Y, Koriyama C, Kinoshita Y, Arita K: Treatable glomerular hyperfiltration in patients with active acromegaly. European Journal of Endocrinology, 2016 Jul 20. pii: EJE-16-0242.

6.Tsukuya G, Samukawa T, Matsumoto K, Fukuyama S, Kumamoto T, Uchida A, Koriyama C, Ninomiya T, Inoue H: Comparison of the COPD Population Screener and International Primary Care Airway Group questionnaires in a general Japanese population: the Hisayama study. International Journal of Chronic Obstructive Pulmonary Disease, 2016, 11:1903-9.

7.Lai HT, Koriyama C, Tokudome S, Tran HH, Tran LT, Nandakumar A, Akiba S, Le NT. Waterpipe tobacco smoking and gastric cancer risk among Vietnamese men. PLoS One. 2016 Nov 1;11(11):e0165587.

8.Toyota M, Saigo Y, Higuchi K, Fujimura T, Koriyama C, Yoshiura T, Akiba S. Comparison of the peripheral doses from different IMRT techniques for pediatric head and neck radiation therapy. Radiat Prot Dosimetry. 2017 Nov;176(3):322-330.

9.Samukawa T, Matsumoto K, Tsukuya G, Koriyama C, Fukuyama S, Uchida A, Mizuno K, Miyahara H, Kiyohara Y, Ninomiya T, Inoue H. Development of a self-scored persistent airflow obstruction screening questionnaire in a general Japanese population: the Hisayama study. International Journal of Chronic Obstructive Pulmonary Disease. 2017, 12:1469-81.

10.Nandakumar A, Uwatoko F, Yamamoto M, Tomita K, Majima H, Akiba S, Koriyama C. Radiation-induced Epstein-Barr virus reactivation in gastric cancer cells with latent EBV infection. Tumor Biology, 2017 Jul; 39(7):1010428317717718.

11. Jinguji M, Nakajo M, Koriyama C, Yoshiura T. Thymic Involution after Radioiodine Therapy for Graves' Disease: Relationships with Serum Thyroid Hormones and TRAb. Journal of the Endocrine Society. 2017 Jun 5;1(7): 852-560.

12. Ko KP, Yeo Y, Yoon JH, Kim CS, Tokudome S, Ngoan LT, Koriyama C, Lim YK, Chang SH, Shin HR, Kang D, Park SK, Kang CH, Yoo KY. Plasma phytoestrogens concentration and risk of colorectal cancer in two different Asian populations. Clinical Nutrition.2018 Oct;37(5):1675-1682.

13.Hoang VAT, Do HTT, Agusa T, Koriyama C, Akiba S, Ishibashi Y, Sakamoto M, Yamamoto M. Hair mercury levels in relation to fish consumption among Vietnamese in Hanoi. The Journal of Toxicological Sciences. 2017, 42(5): 651-662.

14.Matsunaga S, Miyaguchi F, Kawabata N, Kuroshima T, Koriyama C. Cost-effectiveness of therapeutic drugs for the prevention of incident vertebral fracture in patients with postmenopausal osteoporosis -Randomized controlled trial of 72 week follow-up. Journal of Clinical & Experimental Orthopaedics. 2017, 3(3):39.

15.Tran LT, Lai HTM, Koriyama C, Uwatoko F, Akiba S. The association between high birth weight and the risks of childhood CNS tumors and leukemia: an analysis of a US case-control study in an epidemiological database. BMC Cancer. 2017, 17(1):687.

16.Aryal B, Shimizu T, Kadono J, Furoi A, Komokata T, Kitazono I, Koriyama C, Yamakuchi M, Hashiguchi T, Imoto Y. Post-resection exhaustion of intra-platelet serotonin: Also an indicator of early hepatocellular carcinoma recurrence? J Cancer, 2017 Oct 23; 8(19): 3984-3991.

17.Okita S, Daitoku S, Abe M, Arimura E, Setoyama H, Koriyama C, Ushikai M, Kawaguchi H, Horiuchi M. Potential predictors of susceptibility to occupational stress in Japanese novice nurses – a pilot study. Environ Health Prev Med, 2017 Apr 4;22(1):20.

18.Yasuhiro Ishihara, Nami Ikeda-Ishihara, Chihaya Koriyama, Noriaki Kakiuchi, Masayuki Tanaka, Christoph F.A. Vogel, Toshihiro Kawamoto, Tsuji Mayumi. Determination of chemical-specific IgGs in serum by an enzyme-linked immunosorbent assay with partial peptides of human serum albumin. J Toxicol Sci. 2018, 43(1):25-31.

19.Mineshi Sakamoto, Laurie Chan, Jose Domingo, Chihaya Koriyama, Katsuyuki Murata. Kinetics of methylmercury, selenium, vitamin E, and docosahexaenoic acid: maternal and fetal transfer. Environment International, 2018 Feb;111:309-319.

20.Juliet David, Athira Nandakumar, Muflihatul Muniroh, Suminori Akiba, Megumi Yamamoto, Chihaya Koriyama. Suppression of methylmercury-induced MIP-2 expression by N-acetyl-L-cysteine in murine RAW264.7 macrophage cell line. European Journal of Medical Research, 2017 Nov 9;22(1):45.

21.Shintaro Yanazume, Yuji Orita, Chihaya Koriyama, Yuichiro Niihara, Masaki Kamino, Shinichi Togami, Tsutomu Douchi, Hiroaki Kobayashi. Impact of subcutaneous drainage on wound disruption in gynecological malignancy surgery. Kagoshima Journal of Obstetrics and Gynecology, 2017 25: 14-21.

22.Tomoko Ueyama, Takeshi Arimura, Koji Takumi, Fumihiko Nakamura, Ryutaro Higashi, Soichiro Ito, Yoshihiko Fukukura, Tomokazu Umanodan, Masanori Nakajo, Chihaya Koriyama, Takashi Yoshiura. Risk factors for radiation pneumonitis after stereotactic radiation therapy for lung tumours: clinical usefulness of the planning target volume to total lung volume ratio. British Journal of Radiology, 2018 Jun;91 (1086): 20170453.

23.Mayumi Tsuji, Yasuhiro Ishihara, Toyohi Isse, Chihaya Koriyama, Megumi Yamamoto, Noriaki Kakiuchi, Hsu-Sheng Yu, Masayuki Tanaka, Takuto Tsuchiya, Masanori Ohta, Rie Tanaka, Toshihiro Kawamoto. Evaluation of chemical-specific IgG antibodies in male workers from a urethane foam factory. Environmental Health and Preventive Medicine, 2018 23:24.

24.Shinmura K, Choi YH, Shimohira M, Baba Y, Ikeda S, Hayashi S, Shibamoto Y, Koriyama C, Yoshiura T. Comparison of conservative treatment versus transcatheter arterial embolisation for the treatment of spontaneously ruptured hepatocellular carcinoma. Pol J Radiol. 2018 Jun 22;83:e311-e318.

25.Mayumi Tsuji, Eiji Shibata; Seiichi Morokuma; Rie Tanaka; Ayako Senju; Shunsuke Araki; Masafumi Sanefuji; Chihaya Koriyama; Megumi Yamamoto; Yasuhiro Ishihara; Koichi Kusuhara; Toshihiro Kawamoto; Japan Environment & Children's Study Group JECS. The association between whole blood concentrations of heavy metals in pregnant women and premature births: The Japan Environment and Children's Study (JECS). Environmental Research 2018 Oct;166:562-569.

26.Mayumi Tsuji, Chihaya Koriyama, Yasuhiro Ishihara, Christoph F.A. Vogel, Toshihiro Kawamoto. Association between bisphenol A diglycidyl ether-specific IgG in serum and food sensitization in young children. European Journal of Medical Research, 2018 Dec 26;23(1):61.

27.Mayumi Tsuji, Chihaya Koriyama, Yasuhiro Ishihara, Megumi Yamamoto, Kiwako Yamamoto-Hanada, Kumiko Kanatani, Yu Ait Bamai, Kazunari Onishi, Ayako Senju, Shunsuke Araki, Eiji Shibata, Seiichi Morokuma, Masafumi Sanefuji, Hiroshi Kitazawa, Mayako Saito, Masakazu Umezawa, Atsuto Onoda, Koichi Kusuhara, Rie Tanaka, Toshihiro Kawamoto, and the Japan Environment & Children’s Study Group. Associations between metal levels in whole blood and IgE concentrations in pregnant women based on data from the Japan Environment and Children’s Study. Journal of Epidemiology 2019 Dec 5;29(12):478-486.

28.Ananthakrishnakurup Sreekumar, PadmavathyAmma Jayalekshmi, Athira Nandakumar, Raghu Ram K. Nair, Riyaz Ahammed, Paul Sebastian, Chihaya Koriyama, Suminori Akiba, Seiichi Nakamura, Junji Konishi. Thyroid Nodule Prevalence among Women in Areas of High Natural Background Radiation, Karunagappally, Kerala, India. Endocrine 2020 Jan;67(1): 124-130.

29.Kawaike Y, Nagata J, Furuya T, Koriyama C, Nakamura M, Sano A. Working memory-related prefrontal hemodynamic responses in university students: A correlation study of subjective well-being and lifestyle habits. Frontiers in Behavioral Neuroscience 2019, Sep 13;13:213.

30.Aryal B, Yamakuchi M, Shimizu T, Kadono J, Furoi A, Gejima K, Komokata T, Koriyama C, Hashiguchi T, Imoto Y. Predictive value of diminished serum PDGF-BB after curative research of hepatocellular cancer. J Oncology 2019 Jan 6;2019:1925315.

31.Juliet David, Muflihatul Muniroh, Athira Nandakumar, Mayumi Tsuji, Chihaya Koriyama, Megumi Yamamoto. Hg2+- induced MIP-2 expression was suppressed by N-acetyl-L-cysteine in RAW264.7 macrophages. Biomedical Reports 2020 Feb;12(2):39-45.

32.Muflihatul Muniroh, Ainun Rahmasari Gumay, Darmawati Ayu Indraswari, Yuriz Bahtiar, Hardian Hardian, Saekhol Bakri, Nani Maharani, Vega Karlowee, Chihaya Koriyama, Megumi Yamamoto. Activation of MIP-2 and MCP-5 expression in methylmercury-exposed mice and their suppression by N-acetyl-L-cysteine. Neurotoxicity Research 2020 Apr; 37(4):827-834.

33.Sasaki K, Omoto I, Uchikado Y, Okumura H, Noda M, Tsuruda Y, Kita Y, Arigami T, Mori S, Kurahara H, Nakajyo A, Koriyama C, Natsugoe S, Ohtsuka T. Comparison of greater curvature and lesser curvature circular-stapled esophagogastrostomy after esophagectomy in patients with esophageal cancer: a prospective randomized controlled trial. Surg Today 2021 Apr;51(4): 575-581.

34.Kaori Kaimoto, Mikako Yamashita, Taro Suzuki, Hyuma Makizako, Chihaya Koriyama, Takuro Kubozono, Toshihiro Takenaka, Mitsuru Ohishi, Hiroaki Kanouchi, the Tarumizu Study Diet Group. Association of protein and magnesium intake with prevalence of prefrailty and frailty in community-dwelling older Japanese women. J Nutr Sci Vitaminol, 67, 39-47, 2021.

35.Tsunayuki OTSUKA, Kazuhiro UEDA, Tatsuhiko FURUKAWA, Chihaya KORIYAMA, Ituro INOUE, Masami SATO. Significance of Mitochondrial DNA Haplogroup on Epidermal Growth Factor Receptor Mutation in Japanese Patients with Lung Adenocarcinoma. Anticancer Research. 2021 Aug;41(8):3997-4004.

36.Isao Oze, Hidemi Ito, Yumiko Kasugai, Taiki Yamaji, Yuko Kijima, Tomotaka Ugai, Yoshio Kasuga, Tomoyo K. Ouellette, Yukari Taniyama, Yuriko N. Koyanagi, Issei Imoto, Shoichiro Tsugane, Chihaya Koriyama, Motoki Iwasaki, Keitaro Matsuo. A Personal Breast Cancer Risk Stratification Model Using Common Variants and Environmental Risk Factors in Japanese Females. Cancers (Basel). 2021 Jul 28;13(15):3796.

37.Ryo Funatsu, Hiroto Terasaki, Chihaya Koriyama, Satoshi Yamashita, Hideki Shiihara, Taiji Sakamoto. Silicone oil versus gas tamponade for primary rhegmatogenous retinal detachment treated successfully with a propensity score analysis: Japan Retinal Detachment Registry. British Journal of Ophthalmology. 2021 Aug 9: bjophthalmol-2021-319876.

38.Jayalekshmi PadmavathyAmma, Athira Nandakumar, Rekha A Nair, Suminori Akiba, Chihaya Koriyama. Esophageal cancer in relation to alcohol drinking and tobacco use among men in Kerala, India - Karunagappally cohort. Cancer Epidemiology. 2021 Oct;74:102018.

39. Hiroko Indo, Hiromu Ito, Chihaya Koriyama, Hideyuki J. Majima, Kazuyuki Shimada, Yuichi Tamatsu. Deciduous teeth development in fetuses using postmortem computed tomography image analysis. Legal Medicine, 2021 Sep 27:101969.

40.Hiromi Kudo, Shinji Yoshinaga, Xiaoliang Li, Shujie Lei, Shouzhi Zhang, Quanfu Sun, Chihaya Koriyama, Suminori Akiba, Shinji Tokonami. The first attempt to reevaluate radon and thoron exposure in Gansu Province study using radon-thoron discriminative measurement technique. Frontiers in Public Health. 2021 Nov 29; 9:764201.

41.Yuichi Tashiro, Eiji Matsuura, Yasuko Sagara, Satoshi Nozuma, Daisuke Kodama, Masakazu Tanaka, Chihaya Koriyama, Ryuji Kubota, Hiroshi Takashima. High prevalence of HTLV-1 carriers among elderly population in Kagoshima, a highly endemic area in Japan. AIDS Research and Human Retroviruses. 2022 May; 38(5): 363-369.

42.Keita Yamakiri, Taiji Sakamoto, Chihaya Koriyama, Ryo Kawasaki, Takayuki Baba, Koichi Nishitsuka, Takashi Koto, Hiroto Terasaki. Effect of Surgeon-Related Factor on Outcome of Retinal Detachment Surgery: Analyses of Data in Japan-Retinal Detachment Registry. Scientific Reports, 2022 Mar 10; 12(1):4213.

43.Aya Goto, Alison Lloyd Williams, Satoko Okabe, Yohei Koyama, Chihaya Koriyama, Michio Murakami, Yumiya Yui, Kenneth E Nollet. Empowering children as actors in community: Implementing “Creative Health” in primary schools after the Fukushima nuclear disaster. International Journal of Environmental Research and Public Health 2022 Mar 14;19(6):3417.